Shadowing Practice: Journal Highlight: 30-Day Outcomes of Resolute Onyx Stent for Symptomatic Intracranial Stenosis - Learn English Speaking with Video

Ders oluşturuluyor...
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we're presenting 30 -day outcome of Resolute Onyx stent for symptomatic
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intracranial stenosis symptomatic intracranial stenosis is a significant cause of strokes
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and medically refractory patients have higher recurrence rates the only FDA
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approved device at this moment in the United States is wingspan stent which is a bare metal stent two randomized trials,
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Sampras and Casis have demonstrated very high complication rates and no significant relative risk reduction with wingspan stent.
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Newer generation drug eluting stents have shown promise elsewhere such as NOVA trial.
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Resolute Onyx is one such stent which has distinct advantages in navigation and lower drug potency.
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For this multi -center analysis, our key question was, is use of Resolute Onyx stent associated with lower 30 -day risk of major complications in comparison to Sampras data.
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We included patients with recurrent ischemia and stenosis of 70 % to 99 % on best medical management.
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Primary outcome was 30 -day composite of stroke, intracerebral hemorrhage, and death.
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Data from eight comprehensive stroke centers was collected.
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Propensity match groups were created with Sampras medical and stenting.
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This investigation was broken up into three different groups, the Resolute Onyx stent group, the Sampras medical management group, the Sampras stenting group.
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Propensity score match groups were created controlling for age, hyperlipidemia, hypertension, diabetes, and smoking.
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30 -day complication rate of the Resolute Onyx stent was significantly
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lower than the stenting arm of Sampras with an odds ratio of 5 .9.
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The 30 -day complication rate of the Resolute Onyx stent was not statistically different when compared to medical arm of Sampras.
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In conclusion, patients treated with Resoluonix drug -eluting stent had a decreased rate of 30 -day major complications in comparison to Sampras.
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Further, large -scale prospective studies are warranted to evaluate the safety and efficacy of Resoluonix for the treatment of symptomatic intracranial atherosclerosis.
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Given the better safety profile, we will be announcing shortly a prospective multi -center study.
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Thank you.
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Thank you.

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