シャドーイング練習: Gallstones (cholelithiasis) - 動画で英語スピーキングを学ぶ
レッスンを作成中...
1
What?
2
you Gallstones are hard deposits, or simply stones, that form inside the gallbladder.
3
This condition is also known by the Greek name cholelithiasis.
4
"Kola" means bile, "lith" comes from the word lithos meaning stone, and "iasis" refers to an abnormal condition in the body.
5
Put it all together and cholelithiasis means having bile stones.
6
Now, picture yourself enjoying a creamy plate of Greek Musica.
7
As those fats move through your digestive system, they finally reach the small intestine.
8
But fats are difficult to process, and that's where the small, pear -shaped organ gallbladder steps in.
9
Enjoying our Osmosis videos?
10
Unlock your full potential with an Osmosis subscription.
11
Get unlimited access to every Osmosis feature and resource with a free 7 -day trial.
12
The gallbladder acts as a storage tank for bile produced by the liver.
13
The liver carefully blends this digestive smoothie with just the right mix of bile salts, phospholipids, cholesterol, and bilirubin.
14
The liver starts the recipe by converting cholesterol into bile acids such as cholic acid.
15
Then it mixes these bile acids with amino acids like taurine to create water -soluble bile salts
16
that flow smoothly into the bile.
17
But not all cholesterol takes this path.
18
Some slip directly into bile as free cholesterol, where it mixes with bile salts and phospholipids like lecithin.
19
These ingredients act like tiny detergents, wrapping around cholesterol molecules to keep them from crystallizing and clumping.
20
Another key ingredient in bile is bilirubin, which comes from the natural breakdown of red blood cells.
21
When red blood cells reach the end of their life, they release hemoglobin, which is further broken down into heme and globin.
22
The body converts heme into biliverdin and biliverdin to unconjugated bilirubin.
23
However, unconjugated bilirubin isn't water -soluble, so it binds to albumin to hitch a ride to the liver.
24
In the liver, the body transforms unconjugated bilirubin into water -soluble conjugated bilirubin ready for excretion into bile.
25
The liver produces bile continuously, sending it either directly to the small intestine or to the gallbladder for storage.
26
The gallbladder walls, which are lined and coated with protective mucus, absorb water and electrolytes, concentrating the bile up to 10 times its original strength.
27
Most of the time, the liver blends this bile smoothie perfectly.
28
But sometimes, things go off the recipe.
29
the bile becomes too thick, or the gallbladder doesn't empty as it should.
30
That's when gallstones form, and depending on their main ingredient, they can be cholesterol stones and pigmented stones.
31
Cholesterol stones are the most common ones, and they develop exclusively in the gallbladder for several reasons.
32
The main one is supersaturation with cholesterol, which happens when the bile recipe is off.
33
Basically, the liver adds too much free cholesterol, but not enough bile salts and phospholipids.
34
It's like pouring too much protein powder into your smoothie.
35
Instead of blending smoothly, it starts to clump together.
36
The second reason is gallbladder stasis, also known as gallbladder hypomotility, which means the gallbladder isn't contracting the way it should.
37
Just like a smoothie that sits out too long and starts to separate, a stagnant bile gives cholesterol molecules time to clump together.
38
Finally, the gallbladder can produce more mucus than it should.
39
This thick layer creates the perfect environment to trap cholesterol crystals, allowing them to clump together.
40
It's like adding too much syrup to your smoothie.
41
As cholesterol crystals clump together within the gallbladder, they slowly grow into oval and firm cholesterol stones.
42
Sometimes there's just one, but more often there are several stones lying side by side.
43
As they grow, they press against each other and develop flat, smooth surfaces where they touch.
44
When made of pure cholesterol, cholesterol stones have a pale yellow color.
45
However, they can also pick up substances such as calcium carbonate, phosphates, and bilirubin, so their color can range from gray to white or even black.
46
On the other hand, pigment stones make up a smaller portion of gallstones and can appear anywhere along the biliary tree.
47
These stones come in two colors and form when bile contains too much unconjugated bilirubin.
48
Black pigment stones usually form in the sterile bile of the gallbladder and develop in people with chronic hemolytic anemias.
49
In these individuals, high levels of unconjugated bilirubin overwhelm the liver's ability to process it.
50
As a result, unconjugated bilirubin, along with conjugated, appears in bile.
51
Unconjugated bilirubin binds with calcium to form black stones made of calcium bilirubinate, which are usually small, numerous, and fragile to the touch.
52
Next, brownstones usually form in people with biliary tract infections, such as liver flukes.
53
These pathogens often release an enzyme called beta -glucuronidase, which converts conjugated bilirubin back into its unconjugated form.
54
This unconjugated bilirubin then binds with calcium, leading to the formation of brownstones made of calcium bilirubinate.
55
Sometimes they can also include other calcium salts and cholesterol.
56
Compared to black stones, brown stones are usually fewer in number and softer, with a greasy, soap -like texture.
57
This soapy feel comes from another enzyme released by pathogens.
58
It's called phospholipase, which breaks down phospholipids and enables the formation of calcium salts of fatty acids.
59
Several factors can tip the balance toward stone formation.
60
and you can use the mnemonic "magics" to remember them.
61
M stands for metabolic factors, like obesity.
62
A stands for age as risk increases with age, and G represents gallbladder stasis, like an individual's on total parenteral nutrition.
63
Next, I stands for inherited because family history is a risk factor.
64
C stands for childbearing and oral contraceptives, both of which are associated with elevated estrogen levels.
65
Finally, "S" refers to sex because biologically female individuals have a higher risk, again thanks to estrogen activity.
66
Most of the time, gallstones stay silent.
67
But for some, that calm can be shattered by biliary colic, unleashing sharp, intense pain in the upper right abdomen or just below the ribs.
68
Biliary colic typically follows a fatty meal, as fat triggers the gallbladder to contract, pushing a stone against its outlet and causing pressure to build.
69
As pressure rises, the gallbladder walls stretch, making the pain peak within 15 to 60 minutes.
70
The pain holds steady for one to four hours before gradually easing as the stone shifts back or passes through the duct.
71
Often, symptoms like nausea, vomiting, and sweating accompany biliary colic, while people typically feel normal between episodes.
72
Diagnosis primarily relies on abdominal ultrasound, which identifies gallbladder stones in over 90 % of cases.
73
Ultrasound may also show bile duct dilation if a stone has recently passed or is still present.
74
Abdominal x -ray can be done if the cause of the pain is uncertain, but most cholesterol stones are radiolucent and don't show up.
75
However, if they contain calcium salts, such as calcium carbonate, they become radiopaque and visible.
76
Similarly, black pigment stones contain high concentrations of calcium bilirubinate, which makes them radiopaque, while brown pigment stones contain calcium salts of fatty acids,
77
which makes them radiolucent.
78
If needed, you can turn to more advanced tools like Magnetic Resonance Cholangiopancreatography, which maps the bile ducts and identifies stones as filling defects.
79
Also, during the endoscopic retrograde cholangiopancreatography, you can inject dye into the bile ducts and take x -rays to locate stones.
80
If present, you can remove them during the same procedure.
81
Most gallstones don't cause symptoms, so surgery is usually not worth the risks unless they start causing problems.
82
When symptoms do occur, the go -to treatment is laparoscopic cholecystectomy, which is the surgical removal of the gallbladder through small cuts with the help of a tiny camera.
83
For individuals who can't have surgery, alternatives include medications that help dissolve the stones, like ursodeoxycholic acid.
84
Alright, as a quick recap: Gallstones, or colovithiasis, form when substances in bile,
85
primarily cholesterol or unconjugated bilirubin, crystallize within the gallbladder.
86
Cholesterol stones develop if there's too much cholesterol or insufficient bile salts, while pigment stones arise when excess unconjugated bilirubin binds calcium,
87
often due to increased red blood cell breakdown or infections.
88
- Helping current and future clinicians focus, learn, retain, and thrive.
89
Learn more.
📺 同じチャンネル
C13
Pneumothorax - causes, symptoms, diagnosis, treatment, pathology
University StudentsWorking Adults
C14
Nitrates: Nursing Pharmacology
Business EnglishUniversity StudentsWorking Adults
C11
Asthma
University StudentsWorking Adults
C13
Clinical Cuts: B-Cell Activation, Differentiation, & Contraction
IELTS PrepTOEFL PrepCambridge Exam Prep
C12
Myasthenia gravis
University StudentsWorking Adults
C11
Bell palsy
University StudentsWorking Adults
C18
Emotional and mental health needs
Business EnglishUniversity StudentsWorking Adults
C17
Introduction to the immune system
IELTS PrepTOEFL PrepUniversity Students
C1Tuberculosis - causes, symptoms, diagnosis, treatment, pathology
IELTS PrepTOEFL PrepUniversity Students
✨ おすすめ動画
C141 文
Liver Anatomy (Function, Topography, External Structures, Ligaments)
IELTS PrepTOEFL PrepUniversity Students
C11
12 文
Stalagmite and Stalactite
University StudentsWorking Adults
C11
680 文
Helge Ewers Seminar
IELTS PrepTOEFL PrepUniversity Students
C11
18 文
Endoscopic Ultrasound (EUS) Procedure | Cincinnati Children's
University StudentsWorking Adults
C11
155 文
Is Cottage Cheese a GREAT Source of Protein?
Business EnglishUniversity StudentsWorking Adults
C1382
14 文
What Happens When You Eat Too Much Sugar? According To A Sugar Expert
IELTS PrepTOEFL PrepUniversity Students
C11
339 文
Introduction to HPLC - Lecture 1: HPLC Basics
Business EnglishUniversity StudentsWorking Adults
C11
40 文
Hernia Repair Inguinal (Open) Surgery Patient Education
University StudentsWorking Adults
C11
380 文
A man hiked in the woods. Every brain cell got cooked.
IELTS PrepTOEFL PrepUniversity Students
C11
64 文
How Bees Make Honey
University StudentsWorking Adults
C13
177 文
Pediatric Diarrhea – Pediatrics | Lecturio
IELTS PrepTOEFL PrepUniversity Students
このレッスンの語彙とスピーキングのポイント
この動画には、シャドーイング用の文が89文、単語が1339語あります。 音声の長さは10:13です。 話す速さは1分あたり約131語で安定しており、シャドーイングしやすいペースです。 英語の頻出3,000語に含まれる単語は65%だけなので、語彙は難しめです。
この動画の重要語彙
動画に出てくる覚えておきたい単語15語を、発音と意味つきで紹介します。
| 単語 | 発音 | 意味 |
|---|---|---|
| boil 動詞 | /bɔɪ(ə)l/ | 沸かす, 沸騰させる |
| cholesterol 名詞 | /kəˈlɛstəɹɒl/ | コレステロール |
| calcium 名詞 | /ˈkælsi.əm/ | カルシウム, 石灰素 |
| acid 名詞 | /ˈæsɪd/ | 酸 |
| duct 名詞 | /dʌkt/ | ダクト, 導管 |
| blend 動詞 | /blɛnd/ | 混ぜる |
| ingredient 名詞 | /ɪnˈɡɹiːdi.ənt/ | 成分, 原材料 |
| symptom 名詞 | /ˈsɪm(p)təm/ | 症状, 症候 |
| thick 形容詞 | /θɪk/ | 太い, 厚い |
| refer 動詞 | /ɹɪˈfɜː/ | 問い合わせる |
| crystal 名詞 | /ˈkɹɪstəl/ | 結晶 |
| infection 名詞 | /ɪnˈfɛkʃən/ | 伝染 |
| substance 名詞 | /ˈsʌbstəns/ | 物質 |
| breakdown 名詞 | /ˈbɹeɪkˌdaʊn/ | 故障 |
| enzyme 名詞 | /ˈɛn.zaɪm/ | 酵素 |
動画に出てくる句動詞
| 単語 | 意味 |
|---|---|
| pick up 動詞 | 拾う, 拾い上げる |
| show up 動詞 | 現れる |
この動画の文法
話し手がよく使っている文型を、動画の実際の表現とともに紹介します。
| 文型 | 動画での表現 |
|---|---|
| 関係詞節 who / which + 節 — 人や物について情報を加える | hemoglobin, which is · walls, which are · hypomotility, which means |
| 受動態 be + 過去分詞 — 誰がするかより、何が起きるかに焦点を当てる | is also known · are lined · are associated |
注意したい発音
話し手はdon't, isn't, can'tなど、短縮形や弱形を6回使っています。聞こえたとおりの短い形で発音しましょう。
- 「th」の音: thick /θɪk/, smoothly /ˈsmuːðli/, smooth /smuːð/, thrive /θɹajv/, smoothie /ˈsmuːði/
- 「sh」と「zh」の音: infection /ɪnˈfɛkʃən/, sharp /ʃɑɹp/, concentration /ˌkɑn.sənˈtɹeɪ.ʃən/, medication /mɛdɪˈkeɪʃən/, nutrition /njuːˈtɹɪʃ.ən/
- 長い単語（アクセントの位置に注意）: cholesterol /kəˈlɛstəɹɒl/, ingredient /ɪnˈɡɹiːdi.ənt/, primarily /ˈpɹaɪ.mə.ɹə.li/, similarly /ˈsɪm.ə.lə.li/, concentration /ˌkɑn.sənˈtɹeɪ.ʃən/
この動画での練習方法
- まず声を出さずに動画を最後まで聞き、知らない単語をメモします。
- 通常の速度で一文ずつシャドーイングし、話し手のリズムに合うまで繰り返します。
- 自分の声を録音して元の音声と比べます。boil, cholesterol, calciumなどの単語に特に注意しましょう。
シャドーイングとは？英語上達に効果的な理由
シャドーイング（Shadowing）は、もともとプロの通訳者養成プログラムで開発された言語学習法で、多言語習得者として知られるDr. Alexander Arguelles によって広く普及されました。方法はシンプルですが非常に効果的：ネイティブスピーカーの英語を聞きながら、1〜2秒の遅延で声に出してすぐに繰り返す——まるで「影（shadow）」のように話者を追いかけます。文法ドリルや受動的なリスニングと異なり、シャドーイングは脳と口の筋肉が同時にリアルタイムで英語を処理・再現することを強制します。研究により、発音精度、抑揚、リズム、連音、リスニング力、そして会話の流暢さが大幅に向上することが確認されています。IELTSスピーキング対策や自然な英語コミュニケーションを目指す方に特におすすめです。