Shadowing Practice: TOEFL Listening Practice | Lecture | Diabetes - Learn English Speaking with Video

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67 cümleler
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1
Many individuals suffering from the medical condition known as diabetes rely on artificial insulin to maintain good health.
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The principal means of delivering insulin to the body is via injection,
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but work is being done to develop other reliable means of administering it without having to use a syringe.
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Charlotte Newman reports.
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Diabetes is a condition in which the body does not release or properly respond to insulin, a hormone produced in the pancreas.
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Many diabetics require regular insulin injections to regulate their blood glucose levels, in some cases, as many as 10 or more shots a day.
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Although insulin injections allow diabetics to live full and active lives, the treatment does have inherent disadvantages.
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But at Syracuse University in New York, a new delivery method is currently under development.
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Insulin chewing gum.
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Chemist Max Garcia is here to tell us more.
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Well, while many diabetics inject themselves regularly without any real discomfort, some do experience pain and itching where the needle breaks the skin.
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A condition known as lipodystrophy in which the skin puckers can even develop at the site of multiple injections.
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At affected areas, the absorption of insulin may be impaired, making it difficult to calculate the correct dosage.
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Oral delivery of insulin would, therefore, be a preferable treatment.
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But the development of pills
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and capsules has been hampered by various problems relating to the physical and chemical stability of the hormone.
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One major challenge has been to find a way to protect insulin from the hostile conditions in the digestive system.
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Apparently, insulin molecules delivered by mouth will be broken down by the high acidity they encounter in the digestive tract.
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Scientists have tried various strategies to overcome this obstacle.
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And now the team at Syracuse has come up with a potential solution.
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That's right.
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Using their knowledge of the digestive system,
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our scientists realized that the body has a mechanism to protect valuable molecules as they pass through the digestive system.
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So the team decided to chemically bind insulin molecules to vitamin B12,
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A protein called haptocorin, present in the saliva in the mouth,
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joins with this particular vitamin to ensure its safe passage through the stomach to the intestine.
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The research team's idea was simply for the insulin to hitch a ride, as it were, along with a protected vitamin.
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This particular vitamin seems to be a very good choice once
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the b12 reaches the intestine intact another chemical takes over from the haptocorin to help it enter the bloodstream
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so by binding insulin to vitamin b12 the chances of it
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being absorbed into the bloodstream are optimized early tests with rats indicate
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that the researchers are on the right track in these tests the new treatment was administered in liquid form
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but chewing gum would probably be a more efficient medium for human beings.
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Through the chewing action, we could ensure sufficient haptocorin is produced.
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If this solution proves feasible and viable,
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diabetics might one day be able to throw away their syringes and reach for a pack of 1.
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What is one reason why researchers want to find an alternative delivery system for insulin?
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Number 2.
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What difficulty has impeded attempts to develop an oral insulin treatment?
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Number 3.
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What breakthrough did the chemists at Syracuse University make?
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Number 4.
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In which part of the body does haptocorin's protective function end?
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5. What is the current status of the research into chewing gum as a medium for insolent?
45
Number 1.
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What is one reason why researchers want to find an alternative delivery system for insulin?
47
Well, while many diabetics inject themselves regularly without any real discomfort, some do experience pain and itching where the needle breaks the skin.
48
A condition known as lipodystrophy, in which the skin puckers can even develop at the site of multiple injections.
49
Number 2.
50
What difficulty has impeded attempts to develop an oral insulin treatment?
51
Apparently, insulin molecules delivered by mouth will be broken down by the high acidity they encounter in the digestive tract.
52
Scientists have tried various strategies to overcome this obstacle, and now the team at Syracuse has come up with a potential solution.
53
Number three.
54
What breakthrough did the chemists at Syracuse University make?
55
that's right using their knowledge of the digestive system our scientists realized
56
that the body has a mechanism to protect valuable molecules as they pass through the digestive system
57
so the team decided to chemically bind insulin molecules to vitamin b12 a protein called haptocorin,
58
present in the saliva in the mouth, joins with this particular vitamin to ensure its safe passage through the stomach to the intestine.
59
Number 4.
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In which part of the body does haptocorin's protective function end?
61
Once the B12 reaches the intestine intact, another chemical takes over from the haptocorin to help it enter the bloodstream.
62
So by binding insulin to vitamin B12, the chances of it being absorbed into the bloodstream are optimized.
63
Number 5.
64
What is the current status of the research into chewing gum as a medium for insulin?
65
Early tests with rats indicate that the researchers are on the right track.
66
In these tests, the new treatment was administered in liquid form, but chewing gum would probably be a more efficient medium for human beings.
67
Through the chewing action, we could ensure sufficient haptochorin is produced.

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Bu dersin kelimeleri ve konuşma notları

Bu konuşma dersi “TOEFL Listening Practice” videosuna dayanıyor. En çok tekrarlanan kelimeler: insulin, vitamin, digestive, chewing, molecules. Bu videoda gölgeleme çalışması için 67 cümle ve 876 kelime var. Konuşma bölümü 8:29 sürüyor. Konuşmacı yavaş konuşuyor, dakikada yaklaşık 103 kelime; her sesi taklit etmek için zamanınız var. Kelimelerin yalnızca %74’i İngilizcede en sık kullanılan 3.000 kelime arasında, bu yüzden kelime dağarcığı zorlayıcı.

Bu videodaki önemli kelimeler

Videodan öğrenmeye değer 15 kelime, telaffuzu ve anlamıyla:

KelimeTelaffuzAnlam
insulin isim/ˈɪnsəlɪn/insülin
vitamin isim/ˈvɪt.ə.mɪn/vitamin
chew fiil/tʃuː/çiğnemek
molecule isim/ˈmɑ.lɪ.kjul/molekül
injection isim/ɪnˈd͡ʒɛk.ʃən/enjeksiyon
scientist isim/ˈsaɪəntəst/âlim, âlime
researcher isim/ˈɹiˌsɝ.t͡ʃɚ/araştırmacı, araştırıcı
chemist isim/ˈkɛmɪst/kimyacı
efficient sıfat/ɪˈfɪʃənt/verimli
stomach isim/ˈstʌmək/mide, karın
liquid isim/ˈlɪk.wɪd/sıvı, likit
indicate fiil/ˈɪndɪˌkeɪt/belirtmek, göstermek
difficulty isim/ˈdɪfɪkəlti/zorluk
mechanism isim/ˈmɛk.ə.nɪ.zəm/mekanizma
overcome fiil/ˌəʊ.vəˈkʌm/yenmek, atlatmak

Duyacağınız deyimsel fiiller

KelimeAnlam
throw away fiilatmak

Bu videodaki dil bilgisi

Konuşmacının en çok kullandığı yapılar, videodaki sözcüklerin aynısıyla:

YapıVideoda
Edilgen yapı be + fiilin üçüncü hâli — kimin yaptığı değil, ne olduğu önemlibeing done · may be impaired · has been hampered
Present perfect have/has + fiilin üçüncü hâli — geçmişte olan ama şimdi de önemli olan bir eylemhas been hampered · has been · have tried

Dikkat edilecek telaffuzlar

  • “sh” ve “zh” sesleri: injection /ɪnˈd͡ʒɛk.ʃən/, efficient /ɪˈfɪʃənt/, sufficient /səˈfɪʃənt/, artificial /ˌɑː.tɪˈfɪʃ.əl/, absorption /æbˈsɔɹp.ʃn̩/
  • Uzun kelimeler — vurguyu doğru yere koyun: administer /ədˈmɪn.ɪ.stə/, difficulty /ˈdɪfɪkəlti/, mechanism /ˈmɛk.ə.nɪ.zəm/, stability /stəˈbɪlɪti/, artificial /ˌɑː.tɪˈfɪʃ.əl/

Türkçe konuşanların zorlandığı sesler:

  • Kelime başındaki ünsüz kümesi — araya ünlü eklemeyin: stomach /ˈstʌmək/, protective /pɹəˈtɛk.tɪv/, breakthrough /ˈbɹeɪk.θɹuː/, tract /tɹækt/, stability /stəˈbɪlɪti/
  • /æ/ — “e”den daha açık: passage /ˈpæsɪd͡ʒ/, rat /ɹæt/, intact /ɪnˈtækt/, absorb /æbˈsɔɹb/, tract /tɹækt/

Bu videoyla nasıl çalışılır

  1. Videonun tamamını konuşmadan bir kez dinleyin ve bilmediğiniz kelimeleri not edin.
  2. Normal hızda cümle cümle tekrar edin; ritminiz konuşmacıyla aynı olana kadar her cümleyi yineleyin.
  3. Kendinizi kaydedin ve orijinaliyle karşılaştırın; insulin, vitamin, chew gibi kelimelere özellikle dikkat edin.

Gölgeleme Tekniği Nedir?

Gölgeleme, başlangıçta profesyonel tercüman eğitimi için geliştirilen ve çok dilli Dr. Alexander Arguelles tarafından popüler hale getirilen, bilim destekli bir dil öğrenme tekniğidir. Yöntem basit ama güçlüdür: ana dili İngilizce olan bir sesi dinler ve hemen yüksek sesle tekrar edersiniz — konuşmacıyı 1-2 saniye gecikmeyle takip eden bir gölge gibi. Pasif dinleme veya dilbilgisi alıştırmalarının aksine, gölgeleme beyninizi ve ağız kaslarınızı gerçek konuşma kalıplarını eşzamanlı olarak işlemeye ve yeniden üretmeye zorlar. Araştırmalar, telaffuz doğruluğu, tonlama, ritim, bağlı konuşma, dinleme anlama ve konuşma akıcılığını önemli ölçüde geliştirdiğini göstermektedir — bu da onu IELTS Konuşma hazırlığı ve gerçek dünya İngilizce iletişimi için en etkili yöntemlerden biri yapar.

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